The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
<p>Abstract</p> <p>Background</p> <p>Following cleavage by caspase 8, the C-terminus of Bid translocates from the cytosol to the mitochondria that is dependent upon structures formed by the mitochondrial-specific lipid cardiolipin. Once associated with mitochondria, tru...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2001-11-01
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| Series: | BMC Cell Biology |
| Online Access: | http://www.biomedcentral.com/1471-2121/2/22 |