Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.

Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.

FLI1 and ERG, the major ETS transcription factors involved in rearrangements in the Ewing's sarcoma family of tumors (ESFT) and in prostate carcinomas (PCa), respectively, belong to the same subfamily, having 98% sequence identity in the DNA binding domain. We therefore decided to investigate w...

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Bibliographic Details
Main Authors: Maria J Camões, Paula Paulo, Franclim R Ribeiro, João D Barros-Silva, Mafalda Almeida, Vera L Costa, Nuno Cerveira, Rolf I Skotheim, Ragnhild A Lothe, Rui Henrique, Carmen Jerónimo, Manuel R Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3501462?pdf=render

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http://europepmc.org/articles/PMC3501462?pdf=render

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