Participation of liver stem cells in cholangiocarcinogenesis after aflatoxin B exposure of glutathione S-transferase A3 knockout mice
Aflatoxin B 1 , arguably the most potent human carcinogen, induces liver cancer in humans, rats, trout, ducks, and so on, but adult mice are totally resistant. This resistance is because of a detoxifying enzyme, mouse glutathione S-transferase A3, which binds to and inactivates aflatoxin B 1 epoxide...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOS Press
2018-05-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428318777344 |