Implications of Dengue Virus Maturation on Vaccine Induced Humoral Immunity in Mice

Implications of Dengue Virus Maturation on Vaccine Induced Humoral Immunity in Mice

The use of dengue virus (DENV) vaccines has been hindered by the complexities of antibody dependent enhancement (ADE). Current late-stage vaccine candidates utilize attenuated and chimeric DENVs that produce particles of varying maturities. Antibodies that are elicited by preferentially exposed epit...

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Bibliographic Details
Main Authors: Connor A. P. Scott, Alberto A. Amarilla, Summa Bibby, Natalee D. Newton, Roy A. Hall, Jody Hobson-Peters, David A. Muller, Keith J. Chappell, Paul R. Young, Naphak Modhiran, Daniel Watterson
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
dengue
vaccination
ADE
virology
microbiology
flavivirus
Online Access:https://www.mdpi.com/1999-4915/13/9/1843

Internet

https://www.mdpi.com/1999-4915/13/9/1843

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