Involvement of microglia activation in the lead induced long-term potentiation impairment.

Involvement of microglia activation in the lead induced long-term potentiation impairment.

Exposure of Lead (Pb), a known neurotoxicant, can impair spatial learning and memory probably via impairing the hippocampal long-term potentiation (LTP) as well as hippocampal neuronal injury. Activation of hippocampal microglia also impairs spatial learning and memory. Thus, we raised the hypothesi...

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Bibliographic Details
Main Authors: Ming-Chao Liu, Xin-Qin Liu, Wen Wang, Xue-Feng Shen, Hong-Lei Che, Yan-Yan Guo, Ming-Gao Zhao, Jing-Yuan Chen, Wen-Jing Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432044?pdf=render

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http://europepmc.org/articles/PMC3432044?pdf=render

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