Neuroinflammation and protein pathology in Parkinson’s disease dementia

Neuroinflammation and protein pathology in Parkinson’s disease dementia

Abstract Parkinson’s disease dementia is neuropathologically characterized by aggregates of α-synuclein (Lewy bodies) in limbic and neocortical areas of the brain with additional involvement of Alzheimer’s disease-type pathology. Whilst immune activation is well-described in Parkinson’s disease (PD)...

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Bibliographic Details
Main Authors: Antonina Kouli, Marta Camacho, Kieren Allinson, Caroline H. Williams-Gray
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Acta Neuropathologica Communications
Subjects:
Parkinson’s disease dementia
Neuropathology
Neuroinflammation
Microglia
Infiltrating lymphocytes
Pro-inflammatory cytokines
Online Access:https://doi.org/10.1186/s40478-020-01083-5

Internet

https://doi.org/10.1186/s40478-020-01083-5

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