Accelerated postero-lateral spinal fusion by collagen scaffolds modified with engineered collagen-binding human bone morphogenetic protein-2 in rats.

Accelerated postero-lateral spinal fusion by collagen scaffolds modified with engineered collagen-binding human bone morphogenetic protein-2 in rats.

Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive cytokine that plays a critical role in bone regeneration and repair. However, its distribution and side effects are major barriers to its success as therapeutic treatment. The improvement of therapy using collagen delivery matrices has...

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Bibliographic Details
Main Authors: Xinglong Han, Wen Zhang, Jun Gu, Huan Zhao, Li Ni, Jiajun Han, Yun Zhou, Yannan Gu, Xuesong Zhu, Jie Sun, Xianglin Hou, Huilin Yang, Jianwu Dai, Qin Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4037187?pdf=render

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http://europepmc.org/articles/PMC4037187?pdf=render

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