Male subfertility and the risk of major birth defects in children born after in vitro fertilization and intracytoplasmic sperm injection: a retrospective cohort study

Abstract Background Children born after intracytoplasmic sperm injection (ICSI) are at increased risk of specific major birth defects compared with children born after in vitro fertilization (IVF). However, whether this risk is due to the treatment itself (i.e., IVF or ICSI) or underlying male subfe...

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Bibliographic Details
Main Authors: Seung Chik Jwa, Junna Jwa, Akira Kuwahara, Minoru Irahara, Osamu Ishihara, Hidekazu Saito
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12884-019-2322-7