Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans

Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans

Abstract Background The gene encoding a thermostable cellulase of family 12 was previously isolated from a Rhodothermus marinus through functional screening. CelA is a protein of 260 aminoacyl residues with a 28-residue amino-terminal signal peptide. Mature CelA was poorly synthesized in some Escher...

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Bibliographic Details
Main Authors: Mohamed Belal Hamed, Spyridoula Karamanou, Solveig Ólafsdottir, Joana Sofia Martins Basílio, Kenneth Simoens, Kostantinos C. Tsolis, Lieve Van Mellaert, Eik Elísabet Guðmundsdóttir, Gudmundur Oli Hreggvidsson, Jozef Anné, Kristel Bernaerts, Olafur H. Fridjonsson, Anastassios Economou
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Microbial Cell Factories
Subjects:
Cellulase
Protein translocase
Signal peptide
Secretion
Streptomyces lividans
Protein secretion biotechnology
Online Access:http://link.springer.com/article/10.1186/s12934-017-0847-x

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http://link.springer.com/article/10.1186/s12934-017-0847-x

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