Improving Influenza HA-Vlps Production in Insect High Five Cells via Adaptive Laboratory Evolution

The use of non-standard culture conditions has proven efficient to increase cell performance and recombinant protein production in different cell hosts. However, the establishment of high-producing cell populations through adaptive laboratory evolution (ALE) has been poorly explored, in particular f...

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Bibliographic Details
Main Authors: Ricardo Correia, Bárbara Fernandes, Paula M. Alves, Manuel J.T. Carrondo, António Roldão
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/589