Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

SNAREs mediate the formation of a fusion pore during exocytosis which connects the lumen of a vesicle with the extracellular space. Here, authors use single molecule approaches to define the role of synaptotagmin 1 and NSF in synaptic pore formation and dissolution.

Bibliographic Details
Main Authors: Debasis Das, Huan Bao, Kevin C. Courtney, Lanxi Wu, Edwin R. Chapman
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-14072-7