Estimating genomic instability mediated by Alu retroelements in breast cancer

Estimating genomic instability mediated by Alu retroelements in breast cancer

Alu-PCR is a relatively simple technique that can be used to investigate genomic instability in cancer. This technique allows identification of the loss, gain or amplification of gene sequences based on the analysis of segments between two Alu elements coupled with quantitative and qualitative analy...

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Bibliographic Details
Main Authors: Ana Cristina Fazza, Flavia Cal Sabino, Nathalia de Setta, Newton Antonio Bordin Jr., Eloiza Helena Tajara da Silva, Claudia Marcia Aparecida Carareto
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2009-01-01
Series:Genetics and Molecular Biology
Subjects:
Alu-PCR
breast cancer
gene insertions
gene deletions
invasive ductal carcinoma
recombination
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000100004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000100004

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