Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC)

Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC)

Extraintestinal pathogenic Escherichia coli (ExPEC) strains are the cause of a majority of human extraintestinal infections globally, resulting in enormous direct economic and medical costs. The plasmid-mediated, colistin-resistant gene mcr-1 has broken through the ultimate defense line against MDR...

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Bibliographic Details
Main Authors: Hao Lu, Manli Liu, Wenjia Lu, Chenchen Wang, Gaoyan Wang, Wenqi Dong, Xiangru Wang, Huanchun Chen, Chen Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
mcr-1
colistin
ellipticine hydrochloride
ExPEC
multidrug-resistant
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00806/full

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https://www.frontiersin.org/article/10.3389/fmicb.2020.00806/full

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