PMN-MDSC Frequency Discriminates Active Versus Latent Tuberculosis and Could Play a Role in Counteracting the Immune-Mediated Lung Damage in Active Disease

PMN-MDSC Frequency Discriminates Active Versus Latent Tuberculosis and Could Play a Role in Counteracting the Immune-Mediated Lung Damage in Active Disease

Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of death caused by a single infectious agent. The balance between the bacillus and host defense mechanisms reflects the different manifestations of the pathology. Factors defining this variety are unclear an...

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Bibliographic Details
Main Authors: Germana Grassi, Valentina Vanini, Federica De Santis, Alessandra Romagnoli, Alessandra Aiello, Rita Casetti, Eleonora Cimini, Veronica Bordoni, Stefania Notari, Gilda Cuzzi, Silvia Mosti, Gina Gualano, Fabrizio Palmieri, Maurizio Fraziano, Delia Goletti, Chiara Agrati, Alessandra Sacchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
MDSC (myeloid-derived suppressor cell)
tuberculosis
LTBI (latent TB infections)
active TB
monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.594376/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.594376/full

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