Baseline levels of influenza-specific CD4 memory T-cells affect T-cell responses to influenza vaccines.

Factors affecting immune responses to influenza vaccines have not been studied systematically. We hypothesized that T-cell and antibody responses to the vaccines are functions of pre-existing host immunity against influenza antigens.During the 2004 and 2005 influenza seasons, we have collected data...

Full description

Bibliographic Details
Main Authors: Xiao-Song He, Tyson H Holmes, Sanae Sasaki, Maria C Jaimes, George W Kemble, Cornelia L Dekker, Ann M Arvin, Harry B Greenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2440350?pdf=render