The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head

The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head

Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a frequently occurring type of nontraumatic osteonecrosis. A failure of the timely treatment can eventually result in the collapse of the subchondral bone structure. Luteolin (Lut), a compound extracted from Rhizoma Drynariae, is r...

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Bibliographic Details
Main Authors: Zijian Yan, Jingdi Zhan, Weihui Qi, Jian Lin, Yijiang Huang, Xinghe Xue, Xiaoyun Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
glucocorticoid-induced osteonecrosis of the femoral head
luteolin
STAT1/caspase3 pathway
apoptosis
mitochondrial pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01195/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01195/full

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