Preparation and stability investigation of tamsulosin hydrochloride sustained release pellets containing acrylic resin polymers with two different techniques

Preparation and stability investigation of tamsulosin hydrochloride sustained release pellets containing acrylic resin polymers with two different techniques

The objective of this study was to prepare tamsulosin hydrochloride-sustained release (TSH-SR) pellets which showed good release stability with frame-controlled method. TSH was added to Eudragit®NE30D and Eudragit®L30D-55 polymers to form drug-loaded inner core. Afterwards, enteric Eudragit®L30D-55...

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Bibliographic Details
Main Authors: Rui Fan, Yinghua Sun, Bing Li, Ruyi Yang, Wenrui Ma, Jin Sun
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Eudragit®NE30D
Eudragit®L30D-55
Release stability
Temperature
Relative humidity
Coalescence
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300915

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http://www.sciencedirect.com/science/article/pii/S1818087616300915

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