Lactic acidosis associated with metformin in patients with moderate to severe chronic kidney disease: study protocol for a multicenter population-based case-control study using health databases

Abstract Background The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. Methods The ALIMAR-C2 study is a case-control study to assess the associa...

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Bibliographic Details
Main Authors: Consuelo Pedrós, Mónica Ávila, Ainhoa Gómez-Lumbreras, Marcela Manríquez, Rosa Morros, ALIMAR-C2 Study Group
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-019-1389-8