Comparing Effect Estimates in Randomized Trials and Observational Studies From the Same Population: An Application to Percutaneous Coronary Intervention

Comparing Effect Estimates in Randomized Trials and Observational Studies From the Same Population: An Application to Percutaneous Coronary Intervention

Background To understand when results from observational studies and randomized trials are comparable, we performed an observational emulation of a target trial designed to ask similar questions as the VALIDATE (Bivalirudin Versus Heparin in ST‐Segment and Non–ST‐Segment Elevation Myocardial Infarct...

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Bibliographic Details
Main Authors: Anthony A. Matthews, Karolina Szummer, Issa J. Dahabreh, Bertil Lindahl, David Erlinge, Maria Feychting, Tomas Jernberg, Anita Berglund, Miguel A. Hernán
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
methodology
observational studies
randomized controlled trials
registry
SWEDEHEART
target trial emulation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.020357

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.020357

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