Antimesothelioma Immunotherapy by CTLA-4 Blockade Depends on Active PD1-Based TWIST1 Vaccination

Checkpoint immunotherapy is a major breakthrough for cancer treatment, yet its efficacy is often limited against many types of malignancies, including malignant mesothelioma. Considering that the immunotherapeutic efficacy depends on immunosurveillance, we sought to develop an active immunization me...

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Bibliographic Details
Main Authors: Zhiwu Tan, Mei Sum Chiu, Chi Wing Yan, Yik Chun Wong, Haode Huang, Kwan Man, Zhiwei Chen
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030019X