WEE1 inhibition sensitizes osteosarcoma to radiotherapy

<p>Abstract</p> <p>Background</p> <p>The use of radiotherapy in osteosarcoma (OS) is controversial due to its radioresistance. OS patients currently treated with radiotherapy generally are inoperable, have painful skeletal metastases, refuse surgery or have undergone an...

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Bibliographic Details
Main Authors: Helder Marco N, van Beusechem Victor W, Graat Harm CA, Würdinger Thomas, PosthumaDeBoer Jantine, van Royen Barend J, Kaspers Gertjan JL
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/156