KRAS and BRAF mutations in Iranian colorectal cancer patients: A systematic review and meta-analysis

Background: Mutations in the EGFR signaling pathway play an important role in the development of colorectal cancer (CRC). Mutations in these genes, like KRAS and BRAF, affect the treatment strategies and associated with poor prognosis and relative resistance to anti-EGFR therapies. Our aim was to co...

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Bibliographic Details
Main Authors: Abolfazl Yari, Asiyeh Afzali, Mostafa Aalipour, Mehran Nakheai, Mohammad Javad Zahedi
Format: Article
Language:English
Published: Babol University of Medical Sciences 2020-06-01
Series:Caspian Journal of Internal Medicine
Subjects:
crc
Online Access:http://caspjim.com/article-1-1728-en.html