Characterization of the Porcine CLEC12A and Analysis of Its Expression on Blood Dendritic Cell Subsets

Characterization of the Porcine CLEC12A and Analysis of Its Expression on Blood Dendritic Cell Subsets

CLEC12A has been proposed as a suitable target for delivering antigen to dendritic cells (DCs) to enhance vaccine efficacy both in human and mouse. In this study, we have characterized the porcine homolog of CLEC12A (poCLEC12A). Using new monoclonal antibodies (mAb), raised against its ectodomain, p...

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Bibliographic Details
Main Authors: Belén Álvarez, Elvira Nieto-Pelegrín, Paloma Martínez de la Riva, Daisuke Toki, Teresa Poderoso, Concepción Revilla, Hirohide Uenishi, Angel Ezquerra, Javier Domínguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
CLEC12A
C-type lectin
dendritic cell
monoclonal antibody
pig
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00863/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00863/full

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