Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response

Abstract Circulating cell-free DNA (cfDNA) may be involved in immune response regulation. We studied the variations in abundance of telomeric sequences in plasma and serum in young healthy volunteers and the ability of cfDNA contained in these samples to co-activate the TNF-α m RNA expression in mon...

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Bibliographic Details
Main Authors: Alzbeta Zinkova, Iva Brynychova, Alexander Svacina, Marie Jirkovska, Marie Korabecna
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02905-8