Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia

Summary: Microglia have important remodeling functions in neurodevelopment, aging, and disease, with evidence for molecular diversity. However, the signaling pathways and environmental cues that drive diverse states of microglia are incompletely understood. We profiled microglia of a discrete develo...

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Bibliographic Details
Main Authors: Sarah R. Anderson, Jacqueline M. Roberts, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Alejandra Bosco, Monica L. Vetter
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305352