Congenital lipodystrophy induces severe osteosclerosis.

Congenital lipodystrophy induces severe osteosclerosis.

Berardinelli-Seip congenital generalized lipodystrophy is associated with increased bone mass suggesting that fat tissue regulates the skeleton. Because there is little mechanistic information regarding this issue, we generated "fat-free" (FF) mice completely lacking visible visceral, subc...

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Bibliographic Details
Main Authors: Wei Zou, Nidhi Rohatgi, Jonathan R Brestoff, Yan Zhang, Erica L Scheller, Clarissa S Craft, Michael D Brodt, Nicole Migotsky, Matthew J Silva, Charles A Harris, Steven L Teitelbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008244

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https://doi.org/10.1371/journal.pgen.1008244

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