TDP-43 and Limbic-Predominant Age-Related TDP-43 Encephalopathy

Through a number of an extensive autopsy, biomarker, and genomics studies, researchers have recently defined a novel type of dementia known as limbic-predominant age-related TDP-43 encephalopathy (LATE). LATE is perhaps best characterized by the presence of hyperphosphorylated TDP-43, which plays mu...

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Bibliographic Details
Main Authors: Lumi Zhang, Yi Chen, Min Liu, Yunyun Wang, Guoping Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00376/full