Collagenolytic Activity Is Associated with Scar Resolution in Zebrafish Hearts after Cryoinjury

Myocardial infarction is the major cause of cardiac injury in western countries and can result in a massive loss of heart cells, leading eventually to heart failure. A fibrotic collagen-rich scar may prevent ventricular wall rupture, but also may result in heart failure because of its stiffness. In...

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Bibliographic Details
Main Authors: Laurent Gamba, Armaan Amin-Javaheri, Jieun Kim, David Warburton, Ching-Ling Lien
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/4/1/2