Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator.

Cystic fibrosis, an autosomal recessive disorder caused by a mutation in a gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), remains a leading cause of childhood respiratory morbidity and mortality. The respiratory consequences of cystic fibrosis include the generation of...

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Bibliographic Details
Main Authors: Sean V Murphy, Rebecca Lim, Philip Heraud, Marian Cholewa, Mark Le Gros, Martin D de Jonge, Daryl L Howard, David Paterson, Courtney McDonald, Anthony Atala, Graham Jenkin, Euan M Wallace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460882?pdf=render