Oxidized Extracellular DNA as a Stress Signal in Human Cells

The term “cell-free DNA” (cfDNA) was recently coined for DNA fragments from plasma/serum, while DNA present in in vitro cell culture media is known as extracellular DNA (ecDNA). Under oxidative stress conditions, the levels of oxidative modification of cellular DNA and the rate of cell death increa...

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Bibliographic Details
Main Authors: Aleksei V. Ermakov, Marina S. Konkova, Svetlana V. Kostyuk, Vera L. Izevskaya, Ancha Baranova, Natalya N. Veiko
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2013/649747