Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models

Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models

Abstract Background Radiation injury can be indistinguishable from recurrent tumor on standard imaging. Current protocols for this differential diagnosis require one or more follow-up imaging studies, long dynamic acquisitions, or complex image post-processing; despite much research, the inability t...

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Bibliographic Details
Main Authors: Patrick L. Donabedian, Susanne Kossatz, John A. Engelbach, Stephen A. Jannetti, Brandon Carney, Robert J. Young, Wolfgang A. Weber, Joel R. Garbow, Thomas Reiner
Format: Article
Language:English
Published: SpringerOpen 2018-07-01
Series:EJNMMI Research
Subjects:
PET/CT
PARP1
Radiation necrosis
Radiation injury
Amino acid PET
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s13550-018-0399-z

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http://link.springer.com/article/10.1186/s13550-018-0399-z

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