Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes

Summary: Mitochondria are principal metabolic organelles that are increasingly unveiled as immune regulators. However, it is currently not known whether mitochondrial-encoded peptides modulate T cells to induce changes in phenotype and function. In this study, we found that MOTS-c (mitochondrial ope...

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Bibliographic Details
Main Authors: Byung Soo Kong, Se Hee Min, Changhan Lee, Young Min Cho
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008640