Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery

Summary: GPCRs are the largest receptor family that are involved in virtually all biological processes. Pharmacologically, they are highly druggable targets, as they cover more than 40% of all drugs in the market. Our knowledge of biased signaling provided insight into pharmacology vastly improving...

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Bibliographic Details
Main Authors: Mohammad Ali Mohammad Nezhady, José Carlos Rivera, Sylvain Chemtob
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422030835X