Muir-Torre Syndrome Presenting as Sebaceous Adenocarcinoma and Invasive MSH6-Positive Colorectal Adenocarcinoma

Muir-Torre Syndrome Presenting as Sebaceous Adenocarcinoma and Invasive MSH6-Positive Colorectal Adenocarcinoma

Muir-Torre syndrome (MTS) is a rare genodermatosis, diagnosed by the presence of sebaceous neoplasms along with an internal malignancy, most commonly colorectal carcinomas. MTS is most commonly caused by microsatellite instabilities of the hMLH1 and hMSH2 mismatch repair genes, and is rarely caused...

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Bibliographic Details
Main Authors: Sunil Tulpule, Hiyam Ibrahim, Mohamed Osman, Shoaib Zafar, Romana Kanta, Gregory Shypula, Mohammed A. Islam, Shuvendu Sen, Abdalla Yousif
Format: Article
Language:English
Published: Karger Publishers 2016-02-01
Series:Case Reports in Oncology
Subjects:
Sebaceous carcinoma
Muir-Torre syndrome
Hereditary nonpolyposis colon cancer
MSH6
Online Access:http://www.karger.com/Article/FullText/443788

Internet

http://www.karger.com/Article/FullText/443788

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