GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice

The GluA2 subunit in heteromeric AMPA receptor channels restricts Ca2+ permeability and block by polyamines, rendering linear the current-voltage relationship of these glutamate-gated cation channels. Although GluA2-lacking synaptic AMPA receptors occur in GABA-ergic inhibitory neurons, hippocampal...

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Bibliographic Details
Main Authors: Andrei eRozov, Rolf eSprengel, Peter H Seeburg
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00022/full