Increased PARP Activity and DNA Damage in NSCLC Patients: The Influence of COPD

Increased PARP Activity and DNA Damage in NSCLC Patients: The Influence of COPD

(1) <i>Background</i>: Lung cancer (LC) is a major leading cause of death worldwide. Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 are key players in cancer. We aimed to assess PARP-1 and PARP-2 expression and activity and DNA damage in tumors and non-tumor lungs from patients with/wi...

Full description

Bibliographic Details
Main Authors: Jun Tang, Víctor Curull, Xuejie Wang, Coral Ampurdanés, Xavier Duran, Lara Pijuan, Alberto Rodríguez-Fuster, Rafael Aguiló, José Yélamos, Esther Barreiro
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
lung cancer
DNA damage
PARP-1 and PARP-2 expression
PARP activity
COPD
Online Access:https://www.mdpi.com/2072-6694/12/11/3333

Internet

https://www.mdpi.com/2072-6694/12/11/3333

Similar Items