The B. subtilis Accessory Helicase PcrA Facilitates DNA Replication through Transcription Units.

In bacteria the concurrence of DNA replication and transcription leads to potentially deleterious encounters between the two machineries, which can occur in either the head-on (lagging strand genes) or co-directional (leading strand genes) orientations. These conflicts lead to replication fork stall...

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Bibliographic Details
Main Authors: Christopher N Merrikh, Bonita J Brewer, Houra Merrikh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4466434?pdf=render