Mechanism and Function of Antiviral RNA Interference in Mice

Mechanism and Function of Antiviral RNA Interference in Mice

Innate immune sensing of viral nucleic acids in mammals triggers potent antiviral responses regulated by interferons known to antagonize the induction of RNA interference (RNAi) by synthetic long double-stranded RNA (dsRNA). Here, we show that Nodamura virus (NoV) infection in adult mice activates p...

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Bibliographic Details
Main Authors: Qingxia Han, Gang Chen, Jinyan Wang, David Jee, Wan-Xiang Li, Eric C. Lai, Shou-Wei Ding
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
rna interference
antiviral rnai
interferons
plus-strand rna virus
viral suppressor of rnai
Online Access:https://doi.org/10.1128/mBio.03278-19

Internet

https://doi.org/10.1128/mBio.03278-19

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