Systematically Studying the Optimal Amino Acid Distribution Patterns of the Amphiphilic Structure by Using the Ultrashort Amphiphiles

Systematically Studying the Optimal Amino Acid Distribution Patterns of the Amphiphilic Structure by Using the Ultrashort Amphiphiles

Amphipathicity has traditionally been considered to be essential for the de novo design or systematic optimization of antimicrobial peptides (AMPs). However, the current research methods to study the relationship between amphiphilicity and antimicrobial activity are inappropriate, because the key pa...

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Bibliographic Details
Main Authors: Shiqi He, Zhanyi Yang, Weikang Yu, Jiawei Li, Zhongyu Li, Jiajun Wang, Anshan Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptides
amphipathicity
structure-function relationships
antibacterial mechanism
ultrashort amphiphiles
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.569118/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.569118/full

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