The Role of Heparanase in Lymph Node Metastatic Dissemination: Dynamic Contrast-Enhanced MRI of Eb Lymphoma in Mice

Heparanase expression has been linked to increased tumor invasion, metastasis, angiogenesis and with poor prognosis. The aim of the study was to monitor the effect of heparanase expression on lymph node metastasis, in heparanase-overexpressing subcutaneous Eb mouse T-lymphoma tumors, their draining...

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Bibliographic Details
Main Authors: Hagit Dafni, Batya Cohen, Keren Ziv, Tomer Israely, Orit Goldshmidt, Nava Nevo, Alon Harmelin, Israel Vlodavsky, Michal Neeman
Format: Article
Language:English
Published: Elsevier 2005-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800235