Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells

Regulatory T cells (Tregs) play an indispensable role in the prevention of autoimmune disease, as interferon gamma (IFN) mediated, lethal autoimmunity occurs (in both mice and humans) in their absence. In addition, regulatory T cells have been implicated in preventing the onset of autoimmune and a...

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Bibliographic Details
Main Authors: Joseph eLarkin, Chulbul M. Ahmed, Tenisha D. Wilson, Howard M Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00469/full