Targeted Co-Delivery of siRNA and Methotrexate for Tumor Therapy via Mixed Micelles

Targeted Co-Delivery of siRNA and Methotrexate for Tumor Therapy via Mixed Micelles

A combination of chemotherapeutic drugs and siRNA is emerging as a new modality for cancer therapy. A safe and effective carrier platform is needed for combination drug delivery. Here, a functionalized mixed micelle-based delivery system was developed for targeted co-delivery of methotrexate (MTX) a...

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Bibliographic Details
Main Authors: Fei Hao, Robert J. Lee, Chunmiao Yang, Lihuang Zhong, Yating Sun, Shiyan Dong, Ziyuan Cheng, Lirong Teng, Qingfan Meng, Jiahui Lu, Jing Xie, Lesheng Teng
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceutics
Subjects:
drug co-delivery
methotrexate
siRNA
antitumor effect
mixed micelles
targeted delivery system
Online Access:https://www.mdpi.com/1999-4923/11/2/92

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https://www.mdpi.com/1999-4923/11/2/92

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