Association of Toll-Like Receptor 3 Single-Nucleotide Polymorphisms and Hepatitis C Virus Infection

Toll-like receptor 3 (TLR3) plays a key role in innate immunity by recognizing pathogenic, double-stranded RNAs. Thus, activation of TLR3 is a major factor in antiviral defense and tumor eradication. Although downregulation of TLR3 gene expression has been mainly reported in patients infected with h...

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Bibliographic Details
Main Authors: Mashael R. Al-Anazi, Sabine Matou-Nasri, Ayman A. Abdo, Faisal M. Sanai, Saad Alkahtani, Saud Alarifi, Abdullah A. Alkahtane, Hamad Al-Yahya, Daoud Ali, Mohammed S. Alessia, Bushra Alshahrani, Mohammed N. Al-Ahdal, Ahmed A. Al-Qahtani
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2017/1590653