Mesoscopic cortical network reorganization during recovery of optic nerve injury in GCaMP6s mice

Abstract As the residual vision following a traumatic optic nerve injury can spontaneously recover over time, we explored the spontaneous plasticity of cortical networks during the early post-optic nerve crush (ONC) phase. Using in vivo wide-field calcium imaging on awake Thy1-GCaMP6s mice, we chara...

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Bibliographic Details
Main Authors: Marianne Groleau, Mojtaba Nazari-Ahangarkolaee, Matthieu P. Vanni, Jacqueline L. Higgins, Anne-Sophie Vézina Bédard, Bernhard A. Sabel, Majid H. Mohajerani, Elvire Vaucher
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78491-z