Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule

Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule

The elimination of smallpox as an endemic disease and the obvious ethical problems with clinical challenge requires the efficacy evaluation of medical countermeasures against smallpox using the FDA Animal Rule. This approach requires the evaluation of antiviral efficacy in an animal model whose infe...

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Bibliographic Details
Main Authors: Mark R. Perry, Richard Warren, Michael Merchlinsky, Christopher Houchens, James V. Rogers
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
rabbitpox virus
poxvirus
rabbit
animal model
FDA animal rule
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00356/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00356/full

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