Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response ModelSummary

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response ModelSummary

Background & Aims: Heavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreatic acini synthesize digestive enzymes (largely...

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Bibliographic Details
Main Authors: Richard T. Waldron, Hsin-Yuan Su, Honit Piplani, Joseph Capri, Whitaker Cohn, Julian P. Whitelegge, Kym F. Faull, Sugunadevi Sakkiah, Ravinder Abrol, Wei Yang, Bo Zhou, Michael R. Freeman, Stephen J. Pandol, Aurelia Lugea
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18300018

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http://www.sciencedirect.com/science/article/pii/S2352345X18300018

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