Selective Targeting of the Hedgehog Signaling Pathway by PBM Nanoparticles in Docetaxel-Resistant Prostate Cancer

An abnormality in hedgehog (Hh) signaling has been implicated in the progression of prostate cancer (PCa) to a more aggressive and therapy-resistant disease. Our assessments of human PCa tissues have shown an overexpression of the Hh pathway molecules, glioma-associated oncogene homolog 1 (GLI-1), a...

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Bibliographic Details
Main Authors: Santosh Kumar Singh, Jennifer B. Gordetsky, Sejong Bae, Edward P. Acosta, James W. Lillard, Rajesh Singh
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/1976