Propagation of Tau aggregates

Abstract Since 2009, evidence has accumulated to suggest that Tau aggregates form first in a small number of brain cells, from where they propagate to other regions, resulting in neurodegeneration and disease. Propagation of Tau aggregates is often called prion-like, which refers to the capacity of...

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Bibliographic Details
Main Authors: Michel Goedert, Maria Grazia Spillantini
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-017-0298-7