Chalcones and N-acylhydrazones: direct analogues? Exploratory data analysis applied to potential novel antileishmanial agents

Chalcones and N-acylhydrazones: direct analogues? Exploratory data analysis applied to potential novel antileishmanial agents

Leishmaniasis is an important health and social problem for which there is limited effective therapy. Chalcones and N-acylhydrazones have been studied as promising antileishmanial agents in enzymatic inhibition and in vitro assays. Since these chemical classes of compounds also resemble each other s...

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Bibliographic Details
Main Authors: Daniela Gonçalves Rando, Jeanine Giarolla, Kerly Fernanda Mesquita Pasqualoto, Elizabeth Igne Ferreira
Format: Article
Language:English
Published: Universidade de São Paulo 2010-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Chalconas
N-acilidrazonas
Agentes leishmanicidas
Leishmaniose
Quimiometria
Chalcones
N-acylhydrazones
Antileishmanial agents
Leishmaniasis
Chemometrics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200019

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200019

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