Characterization of the early inflammatory infiltrate at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites.

Mice exposed to sand fly saliva are protected against vector-transmitted Leishmania major. Although protection has been related to IFN-γ producing T cells, the early inflammatory response orchestrating this outcome has not been defined.Mice exposed to uninfected P. duboscqi bites and naïve mice were...

Full description

Bibliographic Details
Main Authors: Clarissa Teixeira, Regis Gomes, Fabiano Oliveira, Claudio Meneses, Dana C Gilmore, Dia-Eldin A Elnaiem, Jesus G Valenzuela, Shaden Kamhawi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3998922?pdf=render